绝望的主妇里提到的一种生理现象：Break the seal
Break the seal：1、to tear apart or break up an object which has been wrapped or folded. （拆除或解封某个物体的封条、包装带）；2、used to describe someone can’t help but releasing a feeling or emotion that has been concealing or holding up for quite a long time. （用来描述某种感觉或情绪的爆发）
3、A term used for the first time a person pees when they’re drinking alcohol. When a person who is drunk pees for the first time since being drunk. After they “break the seal” they feel like they have to pee every 5-10 minutes. （用来形容酒喝过多后膀胱积液过多，从下体尿出。）
类似生理现象：Water broke （羊水破了）
Is “breaking the seal”a real thing?
Let’s start with a basic fact when it comes to drinking: What goes in eventually comes out.
So when you’re tipping back glasses of your favorite adult beverage… well, you can only hold in so much. Your body’s reservoir is a pear-sized bladder, after all, not a 5-gallon bucket. Eventually, you have to empty.
The question, though, is when? This is where the myth about a biological barrier known as “the seal” enters the discussion.
The legendary seal is celebrated as a water-tight cap that locks down your bladder. When fully intact, it keeps you from heading to the bathroom to pee. (This ensures that you never miss any fun.)
So what happens when you break that so-called seal and answer nature’s call? Well, you’ve now opened the floodgates and can expect to spend the rest of the night making tracks to the restroom.
In the neon glow of a weekend night, the logic behind this theory seems pretty solid. It doesn’t hold up quite as well under closer (and sober) examination.
Drinking mass quantities of any liquid will inevitably send you to the bathroom, but beer, booze and wine amplify the effect. The reason? Alcohol is a diuretic, which – in the simplest of terms – increases the production of urine.
Breaking it down more, alcohol suppresses the release of an antidiuretic hormone (ADH) called vasopressin. This ADH tells your kidneys to absorb guzzled fluids and distribute to the rest of your body.
But when your brain slows down ADH production during happy hour, the drinks passing by your lips take a more direct route to your bladder. Your bladder only holds about 300 to 400 milliliters of fluid, which is roughly 12 ounces.
It doesn’t take long to exceed your bladder’s capacity. Pressure builds at this point, resulting in the urge to pee. Alcohol also can irritate your bladder, increasing the feeling that you need to tinkle.
So why does it seem like your first bathroom break opens the door to so many return trips? That’s just your body catching up with all the drinks you’ve tipped back during the evening. (Remember the formula: Fluid in = fluid out.)
Holding back on bathroom visits isn’t a good idea, either. Repeatedly preventing the natural flow of things can lead to broader issues, such as urinary tract infections.
If you want to go to the bathroom less during a night out, there’s only one proven way to reduce your trips: drink less. Otherwise, listen to your body and empty your tank before any awkward dancing starts.
Because, to be clear, there is no seal that you’re protecting.
— Urologist Petar Bajic, MD
